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HomeProduct name listHAPTOGLOBIN, HUMAN

HAPTOGLOBIN, HUMAN

Synonym(s):Haptoglobin from human plasma;Haptoglobin, Mixed Type, Human Plasma;Hp

What is HAPTOGLOBIN, HUMAN?

The Uses of HAPTOGLOBIN, HUMAN

Haptoglobin was used to study induction of the acrosome reaction in sperm. Exposure to low temperature increases their rate of fusion with zona-free hamster oocytes.

General Description

Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins.The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains.

Biochem/physiol Actions

Functions by binding to plasma hemoglobin (from hemolysis). The complex is removed from the circulation, by binding to CD163 receptors on macrophages, to salvage iron and prevent oxidative damage.

Properties of HAPTOGLOBIN, HUMAN

storage temp.  -20°C
solubility  H2O: 10 mg/mL, clear to faintly turbid, colorless to almost colorless
form  powder
color  off-white

Safety information for HAPTOGLOBIN, HUMAN

Computed Descriptors for HAPTOGLOBIN, HUMAN

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