HALOPERIDOL DECANOATE
Synonym(s):Decanoic acid 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl ester
- Molecular Weight: 0
- Update Date: 2023-04-23 13:52:06
What is HALOPERIDOL DECANOATE?
The Uses of HALOPERIDOL DECANOATE
Antipsychotic.
brand name
Haldol (Ortho-McNeil).
General Description
Haloperidol decanoate, 4-[4-(4-chlorophenyl)-4-hydroxypiperidino]-4-fluorobutyrophenonedecanoate (Haldol Decanoate), is the decanoate ester(prodrug) of haloperidol. Peak plasma concentrations occurwithin 3 to 9 days and then decrease slowly. Haloperidol decanoatehas no intrinsic activity. Haloperidol decanoate undergoes hydrolysis by plasma and/or tissue esterases toform haloperidol and decanoic acid, subsequently; haloperidolis metabolized in the liver. The pharmacological effectsare those of haloperidol, which is released by bioconversion.Haloperidol decanoate is indicated for the treatment of longtermmaintenance in schizophrenia, psychoses especiallyparanoid, and other mental and behavioral problems.
Properties of HALOPERIDOL DECANOATE
| Melting point: | 42-44°C |
| storage temp. | Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | White |
Safety information for HALOPERIDOL DECANOATE
Computed Descriptors for HALOPERIDOL DECANOATE
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