H-L-Photo-leucine HCl
Synonym(s):Photo-Leu;Photoprobe building block;(S)-2-Amino-3-(3H-diazirin-3-yl)butanoic acid hydrochloride;(S)-2-Amino-3-(3-methyl-3H-diazirin-3-yl)propanoic acid hydrochloride;Diazirine amino acid
- Molecular Weight: 0
- Update Date: 2026-05-28 00:36:55
What is H-L-Photo-leucine HCl?
The Uses of H-L-Photo-leucine HCl
H-L-Photo-leucine HCl is a diazirine-containing leucine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (～360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907391.
Properties of H-L-Photo-leucine HCl
| storage temp. | -20°C |
Safety information for H-L-Photo-leucine HCl
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H242:Self-reactive substances and mixtures; and Organic peroxides |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P234:Keep only in original container. P235:Keep cool. P240:Ground/bond container and receiving equipment. P370+P378:In case of fire: Use … for extinction. P403:Store in a well-ventilated place. |
Computed Descriptors for H-L-Photo-leucine HCl
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