H-Gly-Gly-AMC

CAS NO.：208645-74-3
Empirical Formula: C14H15N3O4
Molecular Weight: 289.29
SAFETY DATA SHEET (SDS)
Update Date: 2025-08-05 17:23:08

What is H-Gly-Gly-AMC?

Description

Gly-Gly-AMC is a fluorogenic peptide substrate. It has been used to assess the activity of bacterial proteases from P. aeruginosa and S. aureus.¹ Activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.

References

1. Wildeboer, D., Jeganathan, F., Price, R.G., et al. Characterization of bacterial proteases with a panel of fluorescent peptide substrates Anal. Biochem. 384(2),321-328(2009).

Properties of H-Gly-Gly-AMC

Boiling point:	650.6±55.0 °C(Predicted)
Density	1.372±0.06 g/cm3(Predicted)
solubility	DMF: 1 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.8 mg/ml
form	A crystalline solid
pka	12.63±0.20(Predicted)

Safety information for H-Gly-Gly-AMC

Computed Descriptors for H-Gly-Gly-AMC

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