GSK466317A

CAS NO.：864082-48-4
Empirical Formula: C21H16ClF3N4O2
Molecular Weight: 448.83
Update Date: 2026-04-21 11:20:27

What is GSK466317A?

Description

GSK466317A is a GRK2 inhibitor. GRK2 has been directly implicated in the progression of heart failure. Selective inhibitors of individual subfamilies of G protein-coupled receptor kinases (GRKs) would serve as useful chemical probes as well as leads for therapeutic applications ranging from heart failure to Parkinson's disease.

Properties of GSK466317A

Boiling point:	713.4±60.0 °C(Predicted)
Density	1.485±0.06 g/cm3(Predicted)
pka	11.54±0.40(Predicted)

Safety information for GSK466317A

Computed Descriptors for GSK466317A

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