GSK-5498A
- CAS NO.：1253186-49-0
- Empirical Formula: C18H11F6N3O
- Molecular Weight: 399.29
- MDL number: MFCD28385869
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-18 09:51:20
What is GSK-5498A?
Definition
ChEBI: GSK-5498A is a member of the class of pyrazoles that is 1H-pyrazole substituted by 2-fluoro-6-(trifluoromethyl)benzyl and (2,6-difluorobenzoyl)amino groups at positions 1 and 3, respectively. It is a inhibitor of Ca(2+) release-activated Ca(2+) (CRAC) channel and inhibits the release of mast cell mediators and T-cell cytokines in human and rat preparations. It has a role as a calcium channel blocker. It is a member of pyrazoles, a secondary carboxamide, a difluorobenzene and a member of (trifluoromethyl)benzenes.
Properties of GSK-5498A
| Boiling point: | 403.3±45.0 °C(Predicted) |
| Density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 100 mg/mL (250.44 mM);Water : < 0.1 mg/mL (insoluble) |
| form | Solid |
| pka | 10.81±0.70(Predicted) |
| color | White to off-white |
Safety information for GSK-5498A
Computed Descriptors for GSK-5498A
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