GSK-3484862
- CAS NO.：2170136-65-7
- Empirical Formula: C19H19N5OS
- Molecular Weight: 365.45
- MDL number: MFCD32708516
- Update Date: 2026-04-22 18:57:36
What is GSK-3484862?
Description
GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer.
in vitro
In total, methylation mapping supports the conclusion that GSK-3484862 treatment produces a drop in DNA methylation consistent with selective and near complete inhibition of DNMT1._x000D_ _x000D_ Reference: Epigenetics Chromatin. 2021 Dec 15;14(1):56. https://pubmed.ncbi.nlm.nih.gov/34906184/
Properties of GSK-3484862
| Boiling point: | 620.5±55.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| solubility | DMSO:20.83(Max Conc. mg/mL);57.0(Max Conc. mM) |
| pka | 14.62±0.50(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
Safety information for GSK-3484862
Computed Descriptors for GSK-3484862
New Products
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