GRP-60367
- CAS NO.：1309241-34-6
- Empirical Formula: C21H27N3O2
- Molecular Weight: 353.46
- MDL number: MFCD19043296
- Update Date: 2026-01-28 14:58:11
What is GRP-60367?
Biological Activity
GRP-60367 is a first-in-class small molecule rabies virus (RABV) entry inhibitor with nanomolar efficacy against certain RABV strains.
in vitro
GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC 50 s ranging from 2 to 52 nM on different host cell lines.
Properties of GRP-60367
| Boiling point: | 547.9±50.0 °C(Predicted) |
| Density | 1.16±0.1 g/cm3(Predicted) |
| pka | 8.44±0.20(Predicted) |
Safety information for GRP-60367
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for GRP-60367
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