Glucose pentaacetate

Synonym(s):1,2,3,4,6-Penta-O-acetyl-α-D-glucopyranose

CAS NO.：604-68-2
Empirical Formula: C16H22O11
Molecular Weight: 390.34
MDL number: MFCD00064071
EINECS: 210-073-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-15 13:03:24

What is Glucose pentaacetate?

Chemical properties

white to light yellow crystal powde

The Uses of Glucose pentaacetate

D-Glucose pentaacetate was reported to stimulate insulin release in rat pancreatic islets. Only α-D-glucose pentaacetate caused an immediate increase in insulin output. The β-anomer of D-glucose pentaacetate first transiently inhibited insulin release, this initial effect being followed by a secondary rise in secretory rate.

What are the applications of Application

α-D-Glucose Pentaacetate is shown to cause an immediate increase in insulin output

What are the applications of Application

Glucose-penta-acetate is a bitter principle in food products, mainly spice blends, condiments, alcoholic beverages, etc. The concentration is equivalent to about 100 to 1500 ppm in the finished consumer product.

Purification Methods

Crystallise it from MeOH, EtOH or three recrystallisations from 95% EtOH. [Wolfrom & Thompson Methods in Carbohydrate Chemistry II 212 1963, Academic Press, Beilstein 17/7 V 318.]

Properties of Glucose pentaacetate

Melting point:	111-113 °C
alpha	97 º (c=1, CHCl3)
Boiling point:	435.58°C (rough estimate)
Density	1.3984 (rough estimate)
vapor pressure	0-0Pa at 20-50℃
FEMA	2524 \| GLUCOSE PENTAACETATE
refractive index	105.5 ° (C=1.5, MeOH)
storage temp.	Sealed in dry,Room Temperature
solubility	chloroform: 0.1 g/mL, clear, colorless
form	Powder
color	White to off-white
Odor	at 100.00 %. odorless
optical activity	[α]20/D ≥+98°, c = 1 in ethanol
Water Solubility	< 5 G/L (25 ºC)
BRN	98852
CAS DataBase Reference	604-68-2(CAS DataBase Reference)
NIST Chemistry Reference	«alpha»-D-Glucopyranose, pentaacetate(604-68-2)
EPA Substance Registry System	.alpha.-D-Glucopyranose, pentaacetate (604-68-2)

Safety information for Glucose pentaacetate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.