GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
- CAS NO.：479065-85-5
- Empirical Formula: C63H83N13O18S2
- Molecular Weight: 1374.54
- MDL number: MFCD04039790
- Update Date: 2026-04-24 14:58:17
What is GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL?
Description
Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from FRAT1, the mammalian version of GSK-3-binding protein. Binds to GSK-3, inhibiting its interaction with axin, and also blocks GSK-3-catalyzed phosphorylation of axin and β-catenin. Does not affect GSK-3-mediated phosphorylation of glycogen synthase or eIF2B.
Properties of GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
| storage temp. | Desiccate at -20°C |
| solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| form | solid |
| color | White lyophilised |
Safety information for GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
Computed Descriptors for GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
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