Glesatinib
- CAS NO.：936694-12-1
- Empirical Formula: C31H27F2N5O3S2
- Molecular Weight: 619.7
- MDL number: MFCD30532644
- Update Date: 2026-04-21 10:31:43
What is Glesatinib?
Description
Glesatinib is a TKI that targets tumors with MET and AXL alterations.
The Uses of Glesatinib
Glesatinib exhibits anti-tumor activity in lung cancer models and patients harboring MET exon 14 mutations and overcomes mutation-mediated resistance.
Clinical Use
Nonclinical models have shown glesatinib to be effective in MET exon 14 skipping mutations. It is currently being evaluated in phase II trials in NSCLC patients with MET alterations.
Properties of Glesatinib
| Density | 1.380±0.06 g/cm3(Predicted) |
| pka | 9.47±0.70(Predicted) |
Safety information for Glesatinib
Computed Descriptors for Glesatinib
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