GGTI-2166
- CAS NO.：478908-51-9
- Empirical Formula: C25H30N4O3
- Molecular Weight: 434.53
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is GGTI-2166?
Description
GGTI-2166 is a geranylgeranyl transferase I inhibitor. GGTI-2166 inhibit the pOC formation induced by RANKL or TNF-alpha in cultures of both mouse marrow-derived macrophage-colony-stimulating factor (M-CSF) dependent monocytes (MD cells) and the mouse monocyte cell line RAW 264.7 (RAW cells). GGTI-2166 inhibited TRAP activity induced by RANKL or TNF-alpha in both cell cultures and prevented the incorporation of [3H]all-trans geranylgeraniol into prenylated proteins in RAW cells.
Safety information for GGTI-2166
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