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HomeProduct name listGalloflavin

Galloflavin

Synonym(s):3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione;NSC 107022

Galloflavin Structural

What is Galloflavin?

The Uses of Galloflavin

Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent.

The Uses of Galloflavin

Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. This compound is suitable for lactate dehydrogenase (LDH) related research.

Biochem/physiol Actions

Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines.

Properties of Galloflavin

Melting point: >140°C (dec.)
Boiling point: 727.6±60.0 °C(Predicted)
Density  2.10±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO: soluble5mg/mL, clear
pka 6.75±0.20(Predicted)
form  powder
color  light yellow to light brown

Safety information for Galloflavin

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Galloflavin

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