FTI-277
- CAS NO.：170006-73-2
- Empirical Formula: C22H29N3O3S2
- Molecular Weight: 447.61
- MDL number: MFCD00952925
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-28 16:00:23
What is FTI-277?
The Uses of FTI-277
Farnesyltransferase inhibitor 277 (FTI-277) has been used to:
- inhibit protein farnesylation in breast cell lines.
- in marrow-isolated adult multilineage inducible cells (MIAMI).
- inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).
Biochem/physiol Actions
Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.
Properties of FTI-277
| Boiling point: | 684.2±55.0 °C(Predicted) |
| Density | 1.222±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: soluble |
| form | amorphous semi-solid |
| pka | 9.81±0.10(Predicted) |
Safety information for FTI-277
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for FTI-277
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