Fmoc-N-Me-Tyr(tBu)-OH
Synonym(s):Fmoc-N-Me-Tyr(tBu)-OH;N-α-Fmoc-N-α-methyl-O-tert-butyl-L-tyrosine
- CAS NO.：133373-24-7
- Empirical Formula: C29H31NO5
- Molecular Weight: 473.56
- MDL number: MFCD02684471
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:06
What is Fmoc-N-Me-Tyr(tBu)-OH?
Chemical properties
White powder
What are the applications of Application
Fmoc-Nalpha-methyl-O-t-butyl-L-tyrosine is an Fmoc protected tyrosine derivative
General Description
Fmoc-N-Me-Tyr(tBu)-OH is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
Synthesis
(9H-Fluoren-9-yl)methyl carbonochloridate could be used as the starting material to synthesize Fmoc-N-Me-Tyr(tBu)-OH.
Properties of Fmoc-N-Me-Tyr(tBu)-OH
| Melting point: | 186-191°C |
| Boiling point: | 638.9±55.0 °C(Predicted) |
| Density | 1.208 |
| storage temp. | 2-8°C |
| pka | 2.98±0.10(Predicted) |
| optical activity | [α]22/D -49.0°, c = 0.5% in DMF |
| CAS DataBase Reference | 133373-24-7(CAS DataBase Reference) |
Safety information for Fmoc-N-Me-Tyr(tBu)-OH
Computed Descriptors for Fmoc-N-Me-Tyr(tBu)-OH
| InChIKey | WTLSDEYZKFJXFT-SANMLTNESA-N |
| SMILES | C(O)(=O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C |
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
Fmoc-N-methyl-O-tert-butyl-L-tyrosine 98.00% CAS 133373-24-7View Details
133373-24-7 -
Fmoc-N-Me-Tyr(tBu)-OH 97% CAS 133373-24-7View Details
133373-24-7 -
Fmoc-N-Me-Tyr(tBu)-OH CAS 133373-24-7View Details
133373-24-7 -
Fmoc-N-Me-Tyr(tBu)-OH CAS 133373-24-7View Details
133373-24-7 -
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8