FMOC-GAMMA-ABU-OH
Synonym(s):4-(Fmoc-amino)butyric acid;Fmoc-GABA
- CAS NO.：116821-47-7
- Empirical Formula: C19H19NO4
- Molecular Weight: 325.36
- MDL number: MFCD00144889
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:29:53
What is FMOC-GAMMA-ABU-OH?
Description
Fmoc-4-aminobutanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-4-aminobutanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical properties
White powder
The Uses of FMOC-GAMMA-ABU-OH
4-(Fmoc-amino)butyric acid is used in agrochemical, pharmaceutical and dyestuff field.
Properties of FMOC-GAMMA-ABU-OH
| Melting point: | 172.0 to 176.0 °C |
| Boiling point: | 571.9±33.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Powder |
| pka | 4.68±0.10(Predicted) |
| color | White |
| Water Solubility | Slightly soluble in water. |
| BRN | 7491485 |
| CAS DataBase Reference | 116821-47-7(CAS DataBase Reference) |
Safety information for FMOC-GAMMA-ABU-OH
Computed Descriptors for FMOC-GAMMA-ABU-OH
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