Fmoc-2-Nal-OH
Synonym(s):Fmoc-3-(2-naphthyl)-L -alanine
- CAS NO.：112883-43-9
- Empirical Formula: C28H23NO4
- Molecular Weight: 437.49
- MDL number: MFCD00144886
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:22
What is Fmoc-2-Nal-OH?
Description
(S)-N-Fmoc-3-(2-naphthyl) alanine is an Fmoc protected form of alanine. Fmoc protected amino acid is quite useful in the solid phase peptide synthesis. Fmoc can be easily removed with piperidine solution without disturbing the acid labile linker between the peptide and the resin. The Fmoc amino acid is also suitable to be analyzed by HPLC due to its high fluorescent activity. Studies have also shown that (S)-N-Fmoc-3-(2-naphthyl) alanine and related peptides have certain inhibitory effect on Staphylococcus virulence.
Chemical properties
white to slightly yellow powder
The Uses of Fmoc-2-Nal-OH
N-Fmoc-3-(2-naphthyl)-L-alanine is used as organic chemical synthesis intermediate.
References
https://www.alfa.com/en/fmoc-protected-compounds/?page=2
http://a2.rqiao.net/patents/US20030050248
Properties of Fmoc-2-Nal-OH
| Melting point: | 155 °C |
| Boiling point: | 549.64°C (rough estimate) |
| Density | 1.2227 (rough estimate) |
| refractive index | 1.6290 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMF (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.77±0.30(Predicted) |
| color | White to Off-White |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 112883-43-9(CAS DataBase Reference) |
Safety information for Fmoc-2-Nal-OH
Computed Descriptors for Fmoc-2-Nal-OH
| InChIKey | JYUTZJVERLGMQZ-SANMLTNESA-N |
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