Flopropione

CAS NO.：2295-58-1
Empirical Formula: C9H10O4
Molecular Weight: 182.17
MDL number: MFCD00016456
EINECS: 218-942-8
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-23 13:58:55

What is Flopropione?

The Uses of Flopropione

antispasmodic

Preparation

Preparation by reaction of propionitrile with phlo-roglucinol (Hoesch reaction);
Preparation by reaction of propionic anhydride with phloroglucinol
in the presence of concentrated sulfuric acid (one drop) at 130° for 5 min ? (65%)
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid ? type) at 160° for 2–3 h (42%). N.B.: Zeokarb 225 was found to be as effective
in the presence of boron trifluoride etherate at 10° (62–65%)
Preparation by reaction of propionyl chloride with phloroglucinol
in the presence of aluminium chloride in nitrobenzene/carbon disulfide ? solution (76%), in nitrobenzene at 60° (55%) or without solvent at 50° (70%)
in the presence of boron trifluoride etherate at 10° (compound ? 3) (62–65%).

Definition

ChEBI: Flopropione is an organic molecular entity.

Properties of Flopropione

Melting point:	177°C
Boiling point:	275.56°C (rough estimate)
Density	1.2481 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in DMSO
pka	7.49±0.45(Predicted)
form	powder to crystal
color	White to Orange to Green
Merck	14,4106
CAS DataBase Reference	2295-58-1(CAS DataBase Reference)
NIST Chemistry Reference	Flopropione(2295-58-1)
EPA Substance Registry System	1-Propanone, 1-(2,4,6-trihydroxyphenyl)- (2295-58-1)