Fingolimod Impurity 8
- CAS NO.：162358-96-5
- Empirical Formula: C16H25I
- Molecular Weight: 344.27
What is Fingolimod Impurity 8?
The Uses of Fingolimod Impurity 8
1-?(2-?Iodoethyl)?-?2-?octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Properties of Fingolimod Impurity 8
| Boiling point: | 363.2±21.0 °C(Predicted) |
| Density | 1.261±0.06 g/cm3(Predicted) |
Safety information for Fingolimod Impurity 8
Computed Descriptors for Fingolimod Impurity 8
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