FERULIC ACID METHYL ESTER

CAS NO.：2309-07-1
Empirical Formula: C11H12O4
Molecular Weight: 208.21
MDL number: MFCD00017208
EINECS: 1308068-626-2
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-05 14:33:18

What is FERULIC ACID METHYL ESTER?

The Uses of FERULIC ACID METHYL ESTER

Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid methyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 74.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). Ferulic acid methyl ester, at 10-25 μg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages.

The Uses of FERULIC ACID METHYL ESTER

Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.

What are the applications of Application

Methyl 4-hydroxy-3-methoxycinnamate is a compound also known as Ferulic acid methyl ester

Definition

ChEBI: A cinnamate ester that is the methyl ester of ferulic acid. It has been isolated from Pisonia aculeata.

Properties of FERULIC ACID METHYL ESTER

Melting point:	62-65°C
Boiling point:	163 °C(Press: 1 Torr)
Density	1.204±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Sparingly), Methanol (
form	Solid
pka	8.88±0.18(Predicted)
color	White to Off-White
Water Solubility	Slightly soluble in water.
CAS DataBase Reference	2309-07-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, methyl ester(2309-07-1)

Safety information for FERULIC ACID METHYL ESTER

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.