Fenipentol

CAS NO.：583-03-9
Empirical Formula: C11H16O
Molecular Weight: 164.25
MDL number: MFCD00021935
EINECS: 209-493-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-04 14:24:59

What is Fenipentol?

Physical properties

White solid lumps or crystalline powder. M.P. 69°C. B.P. 285°C.
Insoluble in water, soluble in alcohol and oils.

Originator

Pancoral,Eisai,Japan,1973

The Uses of Fenipentol

Biliary dyskinesia;Choleretic

Definition

ChEBI: Fenipentol is a member of benzenes.

Production Methods

Fenipentol can be produced by reduction of Valerophenone with Sodium.

Manufacturing Process

The 1-phenylpentanol-(1) may be prepared in any convenient manner. Benzaldehyde may be reacted with n-butyl-magnesium bromide, and after purification 1-phenyl-pentanol-(1) is obtained in the form of a colorless oil at room temperature.

Therapeutic Function

Choleretic

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 5187, 1984 DOI: 10.1016/S0040-4039(01)81559-8

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Stimulates the production of bile by the liver. When heated to decomposition it emits acrid smoke and irritating fumes.

Properties of Fenipentol

Melting point:	<25 °C
Boiling point:	137°C 2mm
Density	0,96 g/cm³
refractive index	1.5080
Flash point:	137°C/2mm
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	14.43±0.20(Predicted)
color	Colorless to Almost colorless
Merck	14,3975
BRN	1908761
CAS DataBase Reference	583-03-9(CAS DataBase Reference)
NIST Chemistry Reference	Fenipentol(583-03-9)
EPA Substance Registry System	Benzenemethanol, .alpha.-butyl- (583-03-9)

Safety information for Fenipentol

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H319:Serious eye damage/eye irritation H372:Specific target organ toxicity, repeated exposure H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.