Ethyl 2-oxocyclopentanecarboxylate
Synonym(s):2-(Ethoxycarbonyl)cyclopentanone;Ethyl cyclopentanone-2-carboxylate
- CAS NO.：611-10-9
- Empirical Formula: C8H12O3
- Molecular Weight: 156.18
- MDL number: MFCD00001412
- EINECS: 210-253-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:55
What is Ethyl 2-oxocyclopentanecarboxylate?
Chemical properties
clear colourless to pale yellow liquid
The Uses of Ethyl 2-oxocyclopentanecarboxylate
Ethyl 2-oxocyclopentanecarboxylate was used in stereoselective synthesis of (±)-cis,cis-spiro[4.4]nonane-1,6-diol. It was also used in the synthesis of tanikolide.
The Uses of Ethyl 2-oxocyclopentanecarboxylate
Pharmaceutical intermediate.
Synthesis Reference(s)
Journal of the American Chemical Society, 85, p. 207, 1963 DOI: 10.1021/ja00885a021
The Journal of Organic Chemistry, 55, p. 5037, 1990 DOI: 10.1021/jo00304a014
Tetrahedron Letters, 22, p. 1353, 1981 DOI: 10.1016/S0040-4039(01)90316-8
General Description
Phase-transfer benzylation reaction of ethyl 2-oxocyclopentanecarboxylate with benzyl bromide in microreactor has been investigated. Ethyl 2-oxocyclopentanecarboxylate participates in cobalt (II) Schiff′s base complex catalyzed oxidation of primary and secondary alcohols.
Hazard
Vapors are toxic, as is skin contact.
Properties of Ethyl 2-oxocyclopentanecarboxylate
| Boiling point: | 102-104 °C/11 mmHg (lit.) |
| Density | 1.054 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 172 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | Liquid |
| pka | 12.02±0.20(Predicted) |
| color | Clear colorless to pale yellow |
| Water Solubility | insoluble |
| BRN | 387787 |
| CAS DataBase Reference | 611-10-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclopentanecarboxylic acid, 2-oxo-, ethyl ester(611-10-9) |
Safety information for Ethyl 2-oxocyclopentanecarboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..… |
Computed Descriptors for Ethyl 2-oxocyclopentanecarboxylate
| InChIKey | JHZPNBKZPAWCJD-UHFFFAOYSA-N |
Ethyl 2-oxocyclopentanecarboxylate manufacturer
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
611-10-9 ethyl-2-oxo-1-cyclooctane carboxylate 98%View Details
611-10-9 -
Ethyl Cyclopentanone-2-carboxylate 611-10-9 98%View Details
611-10-9 -
Ethyl 2-oxocyclopentanecarboxylate CAS 611-10-9View Details
611-10-9 -
Ethyl 2-oxocyclopentanecarboxylate 95% CAS 611-10-9View Details
611-10-9 -
Ethyl 2-oxocyclopentanecarboxylate 97.00% CAS 611-10-9View Details
611-10-9 -
Ethyl 2-Oxocyclopentanecarboxylate CAS 611-10-9View Details
611-10-9 -
Ethyl 2-oxocyclopentanecarboxylate CAS 611-10-9View Details
611-10-9 -
Ethyl 2-oxocyclopentanecarboxylate, Technical Grade, 900mlView Details
611-10-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.