ETH 1001
Synonym(s):(−)-(R,R)-N,N′-Bis-[11-(ethoxycarbonyl)undecyl]-N,N′,4,5-tetramethyl-3,6-dioxaoctane-diamide;(-)-(R,R)-N,Nʹ- bis[11-(Ethoxycarbonyl)undecyl]-N,Nʹ-4,5-tetramethyl-3,6-dioxaoctanediamide, ETH 1001;CA 1001 - CAS 58801-34-6 - Calbiochem;Diethyl N,N′-[(4R,5R)-4,5-dimethyl-1,8-dioxo-3,6-dioxaoctamethylene]bis(12-methylaminododecanoate);ETH 1001
- CAS NO.：58801-34-6
- Empirical Formula: C38H72N2O8
- Molecular Weight: 684.99
- MDL number: MFCD00042943
- EINECS: 261-449-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 19:16:21
What is ETH 1001?
Description
Calcium ionophore I is a Ca2+-selective ionophore for biological membranes that can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca2+ levels.
What are the applications of Application
CA 1001 is a neutral ionophore carrier that exhibits high selectivity for Ca2+ ions
Purification Methods
This is a neutral Ca selectophore. It can be purified by thick layer (2mm) chromatography (Kieselgel F245) and eluted with Me2CO/CHCl3 (2:1). [Ammann et al. Helv Chim Acta 56 1780 1973, Simon & Carafoli Methods Enzymol 56 439 1977.]
References
dagostino m, lee co. neutral carrier na+- and ca2+-selective microelectrodes for intracellular application. biophys j. 1982 dec;40(3):199-207.caroni p, gazzotti p, vuilleumier p, et al. ca2+ transport mediated by a synthetic neutral ca2+ -ionophore in biological membranes. biochim biophys acta. 1977 nov 1;470(3):437-45.hinds tr, vincenzi ff. the effect of eth 1001 on ion fluxes across red blood cell membranes. cell calcium. 1985 jun;6(3):265-79.lücke a, lehmenkühler a, speckmann ej. the influence of the convulsant pentylenetetrazol on ca2+-selective microelectrodes (neutral carrier eth 1001). j neurosci methods. 1989 aug;29(2):139-42.lee mh, yoo cl, lee js, et al. tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. anal chem. 2002 jun 1;74(11):2603-7.
Properties of ETH 1001
| Boiling point: | 715.1±50.0 °C(Predicted) |
| Density | 1.000±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO |
| form | Light yellow, translucent, highly viscous oil |
| pka | -0.52±0.70(Predicted) |
| color | Colorless to light yellow |
| BRN | 2343275 |
Safety information for ETH 1001
Computed Descriptors for ETH 1001
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