Erythromycin A Oxime

Description

(9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .

Chemical properties

Off-White Solid

The Uses of Erythromycin A Oxime

(9E)-Erythromycin A Oxime is a metabolite of Roxithromycin (R700850) in humans. It has anti-Helicobacter pylori activity

The Uses of Erythromycin A Oxime

Intermediate of Azithromycin. Antibacterial agent.

The Uses of Erythromycin A Oxime

Erythromycin A 9-oxime is a semi-synthetic analogue of erythromycin prepared as means of overcoming acid lability and improving oral absorption of erythromycin A while retaining comparable antibacterial and potency. Although not developed as a commercial product, erythromycin oxime was pivotal in the development of the ring expanded aza-erythromycins (e.g. azithromycin) and the oxime ethers (e.g. roxithromycin).

What are the applications of Application

Erythromycin A oxime is a less acid labile analogue of erythromycin with improved oral absorption