Eprazinone
- CAS NO.：10402-90-1
- Empirical Formula: C24H32N2O2
- Molecular Weight: 380.52
- MDL number: MFCD00866843
- EINECS: 233-873-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 15:21:26
What is Eprazinone?
Originator
Mucitux,Riom,France,1969
Definition
ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups.
Manufacturing Process
61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g
(0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and
0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The
product is allowed to crystallize, then filtered and washed with alcohol. It is
dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water.
Yield: 66%. Melting point: 160°C.
Therapeutic Function
Antitussive
Properties of Eprazinone
| Boiling point: | 508.13°C (rough estimate) |
| Density | 1.0909 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 6.83±0.10(Predicted) |
| CAS DataBase Reference | 10402-90-1(CAS DataBase Reference) |
Safety information for Eprazinone
Computed Descriptors for Eprazinone
New Products
N,O-Dimethylhydroxylamine hydrochloride Tetrabutylammonium perchlorate N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile Imatinib Impurity Brivaracetam Racemic Acid Balcofen S- isomer/(S)-Baclofen Lansoprazole S-Isomer R,S,S-diketopiperazine (EP & USP)/Lisinopril EP Impurity D Vildagliptin N-Nitroso-L-Proline Methyl Ester 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide valeronitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
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