Epitiostanol
- CAS NO.：2363-58-8
- Empirical Formula: C19H30OS
- Molecular Weight: 306.51
- MDL number: MFCD00866499
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:58
What is Epitiostanol?
Originator
Thiodrol,Shionogi,Japan,1977
The Uses of Epitiostanol
An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.
Definition
ChEBI: Epitiostanol is an organic molecular entity.
Manufacturing Process
A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.
Therapeutic Function
Antineoplastic
Properties of Epitiostanol
| Melting point: | 127-128° |
| Boiling point: | 417.1°C (rough estimate) |
| alpha | D27.5 +24.4° (c = 1.054 in chloroform) |
| Density | 1.0122 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 15.10±0.60(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 1.2mg/L(37 ºC) |
Safety information for Epitiostanol
Computed Descriptors for Epitiostanol
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