Ecabet sodium
- CAS NO.：86408-72-2
- Empirical Formula: C20H29NaO5S
- Molecular Weight: 404.5
- MDL number: MFCD00866896
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is Ecabet sodium?
Description
Ecabet sodium is a new antiulcer agent launched in Japan for the treatment of gastric ulcer. It has both mucosal-protective and tissue-repairing properties. In rats, it effectively prevents gastrointestinal lesion formation induced experimentally by EtOH, HCl, NaOH, and boiling water. The mechanism of action has been suggested to involve inhibition of pepsin activity in gastric juice by precipitating pepsin in the form of a complex and inactivating pepsinogen.
Originator
Tanabe (Japan)
brand name
Gastrom
Properties of Ecabet sodium
| Melting point: | >300° |
| alpha | D20 +59.4° (c = 0.5) |
| storage temp. | Store at -20°C |
| solubility | DMF: 25 mg/ml; DMSO: 30 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 3 mg/ml |
| form | A crystalline solid |
| color | White to off-white |
Safety information for Ecabet sodium
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ecabet sodium
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