EC 5.4.2.2
Synonym(s):α-D -Glucose-1,6-bisphosphatase;α-D -Glucose-1-phosphate phosphotransferase
- CAS NO.：9001-81-4
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00131886
- EINECS: 232-634-0
- Update Date: 2026-01-13 11:18:30
What is EC 5.4.2.2?
Chemical properties
White to light yellow solid
The Uses of EC 5.4.2.2
Phosphoglucomutase exchanges a phosphoryl group with the substrate.
The Uses of EC 5.4.2.2
Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.
General Description
The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with unique four-domain architecture.
Biochem/physiol Actions
Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.
Properties of EC 5.4.2.2
| Density | 1.00 g/mL at 20 °C |
| storage temp. | -20°C |
| form | ammonium sulfate suspension |
| color | White to off-white |
| EPA Substance Registry System | Phosphomutase, glucose (9001-81-4) |
Safety information for EC 5.4.2.2
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for EC 5.4.2.2
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