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HomeProduct name listEC 3.4.14.1

EC 3.4.14.1

Synonym(s):Dipeptidyl aminopeptidase;Dipeptidyl peptidase I

  • CAS NO.:9032-68-2
  • Molecular Weight: 0
  • MDL number: MFCD00081490
  • EINECS: 232-881-4
  • Update Date: 2026-01-13 11:22:22

What is EC 3.4.14.1?

The Uses of EC 3.4.14.1

The enzyme from Sigma has been used in the activation of granzyme k (Gzmk) precursor from E. coli. Granzymes are granule-stored lymphocyte serine proteases that are implicated in T- and natural killer cell-mediated cytotoxic defense reactions.

Biochem/physiol Actions

Cathespin C is a dipeptidyl aminopeptidase that can sequentially remove dipeptides from a peptide chain with an unsubstituted N-terminus. The enzyme exhibits a preference for glycine and proline as N-terminal aminoacids. Substrates that have an N-terminal lysyl or arginyl residue, or a penultimate proryl residue are not targeted by this enzyme. The endopeptidase activity requires the presence of halide ions and sulfydryl activators.

Properties of EC 3.4.14.1

storage temp.  -20°C
form  lyophilized powder

Safety information for EC 3.4.14.1

Computed Descriptors for EC 3.4.14.1

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