E3 ligase Ligand-Linker Conjugates 5 Free Base
- CAS NO.：2010159-56-3
- Empirical Formula: C30H45N5O7S
- Molecular Weight: 619.77
- MDL number: MFCD31727698
- Update Date: 2025-04-18 09:51:43
What is E3 ligase Ligand-Linker Conjugates 5 Free Base?
Description
(S, R, S)-AHPC-PEG3-amine hydrochloride salt is comprised of VHL Ligand coupled to an amine via a PEG3 linker. The 1 VHL Ligand 1 is a synthetic compound used in PROTAC research based on E3 ligase ligand. NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC , or directly with NHS esters, to form a stable amide bond.
Properties of E3 ligase Ligand-Linker Conjugates 5 Free Base
| Boiling point: | 879.2±65.0 °C(Predicted) |
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| pka | 13.54±0.46(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
Safety information for E3 ligase Ligand-Linker Conjugates 5 Free Base
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for E3 ligase Ligand-Linker Conjugates 5 Free Base
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