(E)-2-Butenoyl chloride

CAS NO.：625-35-4
Empirical Formula: C4H5ClO
Molecular Weight: 104.53
MDL number: MFCD00000734
EINECS: 234-010-3
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:16:25

What is (E)-2-Butenoyl chloride?

Chemical properties

clear colourless to brown liquid

The Uses of (E)-2-Butenoyl chloride

Crotonyl chloride is used in agrochemical, pharmaceutical and dyestuff field. Crotonoyl chloride was used in the synthesis of α,β-unsaturated ester.

Purification Methods

If the IR of a film has no OH bands, then fractionally distil it, taking the middle fraction and redistilling it. If OH bands are present, then add excess of oxalyl chloride, reflux for 3hours, then distil off the reagent and fractionally distil the crotonoyl chloride as before. Stabilise the distillate with 160ppm of hydroquinone. The amide forms needles m 158o from aqueous ammonia, and the anilide also forms needles but with m 115-118o from H2O. [Beilstein 2 H 411, 2 I 188, 2 II 392, 2 III 1265, 2 IV 1506.]

Properties of (E)-2-Butenoyl chloride

Melting point:	72-74 °C
Boiling point:	120-123 °C(lit.)
Density	1.091 g/mL at 25 °C(lit.)
refractive index	n20/D 1.459(lit.)
Flash point:	95 °F
storage temp.	2-8°C
form	Liquid
color	Clear colorless to brown
Water Solubility	Reacts with water.
Sensitive	Moisture Sensitive
BRN	506118
CAS DataBase Reference	625-35-4(CAS DataBase Reference)
NIST Chemistry Reference	2-Butenoyl chloride, (E)-(625-35-4)

Safety information for (E)-2-Butenoyl chloride

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H314:Skin corrosion/irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.