Doxycycline hydrochloride
Synonym(s):α-6-Deoxy-5-hydroxytetracycline hydrochloride;Doxylin;Idocyklin;Vibramycin hyclate;Vibramycin hydrochloride
- CAS NO.:10592-13-9
- Empirical Formula: C22H25ClN2O8
- Molecular Weight: 480.9
- MDL number: MFCD03427564
- EINECS: 234-198-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-07 19:09:50
What is Doxycycline hydrochloride?
Chemical properties
Yellow Crystalline powder
The Uses of Doxycycline hydrochloride
Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.
The Uses of Doxycycline hydrochloride
antibiotic
The Uses of Doxycycline hydrochloride
Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.
Definition
ChEBI: The hydrochloride salt of doxycycline.
Properties of Doxycycline hydrochloride
| Melting point: | 195-201℃ |
| Flash point: | 87℃ |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 50 mg/mL, clear, yellow-green |
| form | powder |
| color | yellow |
| Water Solubility | Soluble in water. |
| CAS DataBase Reference | 10592-13-9(CAS DataBase Reference) |
Safety information for Doxycycline hydrochloride
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 ![]() Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Doxycycline hydrochloride
| InChIKey | RUYHIJHUVHIMIR-PGTYNCOMNA-N |
| SMILES | O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r| |
Doxycycline hydrochloride manufacturer
Crystal Pharma
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