Dorzolamide Hydrochloride
Synonym(s):Dorzolamide hydrochloride
- CAS NO.：130693-82-2
- Empirical Formula: C10H17ClN2O4S3
- Molecular Weight: 360.9
- MDL number: MFCD00884659
- EINECS: 620-304-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-20 22:47:09
What is Dorzolamide Hydrochloride?
Description
Dorzolamide hydrochloride was introduced in the U.S.A. as eye drops for the treatment of open-angle glaucoma and ocular hypertension. Dorzolamide is a potent carbonic anhydrase inhibitor that, on topical administration, lowers intraocular pressure (IOP). In a clinical study in patients with bilateral primary open-angle glaucoma or ocular hypertension, dorzolamide (0.7-2%) was found to significantly lower IOP throughout the day. Dorzolamide has been shown to be effective as a single therapy or in combination with β-blockers.
The Uses of Dorzolamide Hydrochloride
Carbonic anhydrase inhibitor. Antiglaucoma agent.
What are the applications of Application
Dorzolamide Hydrochloride is an inhibitor of carbonic anhydrase
Properties of Dorzolamide Hydrochloride
| Melting point: | 265-2670C |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol. |
| form | neat |
| color | White to Off-White |
Safety information for Dorzolamide Hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Dorzolamide Hydrochloride
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