DoPAT

Synonym(s):2-(Dodecylthiocarbonothioylthio)propanoic acid;2-{[(Dodecylsulfanyl)carbonothioyl]sulfanyl}propanoic acid;DoPAT

CAS NO.：558484-21-2
Empirical Formula: C16H30O2S3
Molecular Weight: 350.6
MDL number: MFCD22200510
Update Date: 2026-06-19 07:28:27

What is DoPAT?

The Uses of DoPAT

RAFT agent for controlled radical polymerization; especially suited for the polymerization of styrene, acrylate and acrylamide monomers. Chain Transfer Agent (CTA)

Definition

2-(Dodecylthiocarbonothioylthio)propionic acid (DoPAT) is a trithiocarbonate reversible addition–fragmentation chain transfer (RAFT) agent. DADMAC was polymerized in aqueous solution employing 2,2′-azobis(2-methylpropionamidine)-dihydrochloride as the free-radical initiator and DoPAT as the controlling RAFT agent. 2-(Dodecylthiocarbonothioylthio)propionic acid could only be activated under blue light[1-2].

General Description

Need help choosing the correct RAFT Agent? Please consult the RAFT Agent to Monomer compatibility table.

References

[1] James P. Blinco . “Living characteristics of the free-radical ring-closing polymerization of diallyldimethylammonium chloride.” European Polymer Journal 47 1 (2011): Pages 111-114.
[2] Sivaprakash Shanmugam. “Catalyst-Free Selective Photoactivation of RAFT Polymerization: A Facile Route for Preparation of Comblike and Bottlebrush Polymers.” Macromolecules 51 19 (2018): 7776–7784.

Properties of DoPAT

Melting point:	78-82℃
Boiling point:	499.5±24.0 °C(Predicted)
Density	1.093±0.06 g/cm3(Predicted)
storage temp.	2-8°C
form	powder or crystals
pka	2.93±0.10(Predicted)
InChI	InChI=1S/C16H30O2S3/c1-3-4-5-6-7-8-9-10-11-12-13-20-16(19)21-14(2)15(17)18/h14H,3-13H2,1-2H3,(H,17,18)

Safety information for DoPAT

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for DoPAT

InChIKey	CFCFZJHCTNKHGJ-UHFFFAOYSA-N
SMILES	C(O)(=O)C(SC(SCCCCCCCCCCCC)=S)C

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