DMPAC-Chol
- CAS NO.：184582-91-0
- Empirical Formula: C33H58N2O2
- Molecular Weight: 514.84
- Update Date: 2026-04-22 18:57:36
What is DMPAC-Chol?
Description
DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml.
Properties of DMPAC-Chol
| Boiling point: | 591.2±39.0 °C(Predicted) |
| Density | 1.01±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF:10.0(Max Conc. mg/mL);19.42(Max Conc. mM) Ethanol:10.0(Max Conc. mg/mL);19.42(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.27(Max Conc. mM) |
| form | A crystalline solid |
| pka | 12.49±0.46(Predicted) |
Safety information for DMPAC-Chol
Computed Descriptors for DMPAC-Chol
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