DL-Pipecolinic acid
Synonym(s):(±)-Piperidine-2-carboxylic acid;2-Piperidinecarboxylic acid;Homoproline;Pipecolic acid free base
- CAS NO.：535-75-1
- Empirical Formula: C6H11NO2
- Molecular Weight: 129.16
- MDL number: MFCD00064347
- EINECS: 208-616-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:59:12
What is DL-Pipecolinic acid?
Chemical properties
white to light beige fine crystalline powder
The Uses of DL-Pipecolinic acid
DL-Pipecolinic acid is used as a diagnostic marker of pyridoxine-dependent epilepsy. It acts as a ligand in copper-catalyzed approach for P-arylation of organophosphorus compounds. It is used as organocatalyst and novel substrate in organic synthesis.
The Uses of DL-Pipecolinic acid
Pipecolic acid is involved in synaptic transmission in the central nervous system.
Definition
ChEBI: A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
Properties of DL-Pipecolinic acid
| Melting point: | 282 °C (dec.)(lit.) |
| Boiling point: | 239.22°C (rough estimate) |
| alpha | [α]D20 -1～+1° (c=2.5, H2O) |
| Density | 1.1426 (rough estimate) |
| refractive index | 1.4587 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 2.28, 10.72(at 25℃) |
| form | Fine Crystalline Powder |
| color | White to light beige |
| Water Solubility | soluble |
| Merck | 14,7458 |
| BRN | 81095 |
| CAS DataBase Reference | 535-75-1(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Piperidinecarboxylic acid (535-75-1) |
Safety information for DL-Pipecolinic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DL-Pipecolinic acid
| InChIKey | HXEACLLIILLPRG-UHFFFAOYSA-N |
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