DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
Synonym(s):Diethyl phosphonoacetaldehyde diethyl acetal;NSC 407851;NSC 77101
- CAS NO.：7598-61-0
- Empirical Formula: C10H23O5P
- Molecular Weight: 254.26
- MDL number: MFCD00009236
- EINECS: 231-504-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:13
What is DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE?
Chemical properties
Colourless Oil
The Uses of DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
Diethyl 2,2-diethoxyethylphosphonate can be used as a useful wittig reagent.
The Uses of DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
Diethyl 2,2-diethoxyethylphosphonate is used reactant for synthesis of α,β-alkenal derivatives by two-carbon homologation, lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions, α-Phosphovinyl radicals via a radical trapping sequence, inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions and for Friedel-Crafts reactions.
The Uses of DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
Reactant for synthesis of:
- α,β-Alkenal derivatives by two-carbon homologation
- Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
- α-Phosphovinyl radicals via a radical trapping sequence
- Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions
Reactant for Friedel-Crafts reactions
What are the applications of Application
Diethyl 2,2-Diethoxethylphosphonate is a useful wittig reagent
Properties of DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
| Boiling point: | 146-149 °C14 mm Hg(lit.) |
| Density | 1.052 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Dichloromethane |
| form | Oil |
| color | Colourless |
| Water Solubility | Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water. |
| Sensitive | Moisture Sensitive |
| BRN | 1785614 |
| CAS DataBase Reference | 7598-61-0(CAS DataBase Reference) |
Safety information for DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DIETHYL 2,2-DIETHOXYETHYLPHOSPHONATE
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