Dideoxyadenosine
Synonym(s):2′,3′-Dideoxyadenosine;ddA
- CAS NO.：4097-22-7
- Empirical Formula: C10H13N5O2
- Molecular Weight: 235.24
- MDL number: MFCD00010534
- EINECS: 223-853-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Dideoxyadenosine?
Chemical properties
Beige power
The Uses of Dideoxyadenosine
2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.
The Uses of Dideoxyadenosine
A potent labelled anti-HIV agent.
The Uses of Dideoxyadenosine
A potent anti-HIV agent.
The Uses of Dideoxyadenosine
Dideoxy Adenosine (Didanosine EP Impurity G) is a potent anti-HIV agent.
What are the applications of Application
2′,3′-Dideoxyadenosine is an inhibitor of adenylate cyclase and adenosine deaminase
Definition
ChEBI: A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine.
General Description
Off-white powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
Dideoxyadenosine may be sensitive to prolonged exposure to light.
Health Hazard
SYMPTOMS: Symptoms of exposure to a related compound include cutaneous eruptions, fever, mouth sores, thrombocytopenia, neutropenia, reversible peripheral neuropathy, gastrointestinal distress, headache, nausea and vomiting.
Fire Hazard
Flash point data for Dideoxyadenosine are not available; however, Dideoxyadenosine is probably combustible.
Properties of Dideoxyadenosine
| Melting point: | 181-184 °C(lit.) |
| Boiling point: | 377.64°C (rough estimate) |
| alpha | D25 -25.2° (c = 1.01 in water) |
| Density | 1.2455 (rough estimate) |
| refractive index | -34 ° (C=1, H2O) |
| storage temp. | -20°C |
| solubility | DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble |
| pka | pKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain) |
| form | Powder |
| color | White to Off-white |
| Water Solubility | 43.2g/L(25 ºC) |
| Merck | 14,3101 |
| BRN | 619924 |
| CAS DataBase Reference | 4097-22-7(CAS DataBase Reference) |
| EPA Substance Registry System | Adenosine, 2',3'-dideoxy- (4097-22-7) |
Safety information for Dideoxyadenosine
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H303:Acute toxicity,oral H341:Germ cell mutagenicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Dideoxyadenosine
| InChIKey | WVXRAFOPTSTNLL-NKWVEPMBSA-N |
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