DEHYDRO ARIPIPRAZOLE
Synonym(s):7-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}quinolin-2(1H)-one;Dehydroaripiprazole
- CAS NO.：129722-25-4
- Empirical Formula: C23H25Cl2N3O2
- Molecular Weight: 446.37
- MDL number: MFCD00892073
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-20 19:14:41
What is DEHYDRO ARIPIPRAZOLE?
The Uses of DEHYDRO ARIPIPRAZOLE
Dehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.
General Description
Dehydro Aripiprazole is the primary, active metabolite of aripiprazole, marketed as the atypical antipsychotic Abilify? for the treatment of schizophrenia, bipolar disorder, and clinical depression. This new certified solution standard is suitable for use in LC or GC applications including forensic or clinical toxicology analysis and urine drug testing.
Properties of DEHYDRO ARIPIPRAZOLE
| Melting point: | >139oC (dec.) |
| Boiling point: | 654.4±55.0 °C(Predicted) |
| Density | 1.281±0.06 g/cm3(Predicted) |
| Flash point: | 349℃ |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 11.22±0.70(Predicted) |
| color | White to Off-White |
Safety information for DEHYDRO ARIPIPRAZOLE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H290:Corrosive to Metals H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
Computed Descriptors for DEHYDRO ARIPIPRAZOLE
| InChIKey | CDONPRYEWWPREK-UHFFFAOYSA-N |
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