D-Phenylglycinol
Synonym(s):(R)-2-Amino-2-phenylethanol;D -(−)-α-Phenylglycinol
- CAS NO.：56613-80-0
- Empirical Formula: C8H11NO
- Molecular Weight: 137.18
- MDL number: MFCD00008062
- EINECS: 260-287-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:55
What is D-Phenylglycinol?
Chemical properties
white to light yellow crystal powder.
The Uses of D-Phenylglycinol
As a chiral arylalkylamine used as organocatalysts, D-Plenylglycinol can be used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.
The Uses of D-Phenylglycinol
A chiral arylalkylamine used as organocatalysts. Used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.
What are the applications of Application
(R)-(?)-2-Phenylglycinol is a useful stereodefined starting material
Definition
ChEBI: (R)-(-)-2-Phenylglycinol is an aralkylamine.
Preparation
D-Phenylglycinol was synthesized by reducing D-phenylglycine using a sodium borohydride-iodine system. The best reaction conditions were using tetrahydrofuran as the solvent, a 1:2 ratio of D-phenylglycine to sodium borohydride, a hydrolysis temperature of 50°C, and a reaction time of 20 hours.
Properties of D-Phenylglycinol
| Melting point: | 76-79 °C |
| Boiling point: | 252.03°C (rough estimate) |
| alpha | -25.5 º (c=6,MeOH) |
| Density | 1.0630 (rough estimate) |
| refractive index | -29.5 ° (C=1, EtOH) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Aqueous Acid (Slightly, Sonicated), Chloroform (Sparingly, Heated), Methanol (Slightly) |
| pka | 12.51±0.10(Predicted) |
| form | Crystalline Powder |
| color | White to yellow |
| optical activity | [α]24/D 31.7°, c = 0.76 in 1 M HCl |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Air Sensitive |
| BRN | 2935848 |
| CAS DataBase Reference | 56613-80-0(CAS DataBase Reference) |
| NIST Chemistry Reference | (R)-(-)-2-phenylglycinol(56613-80-0) |
Safety information for D-Phenylglycinol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for D-Phenylglycinol
| InChIKey | IJXJGQCXFSSHNL-QMMMGPOBSA-N |
D-Phenylglycinol manufacturer
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