D-GLUCOHEPTONO-1,4-LACTONE
- CAS NO.：60046-25-5
- Empirical Formula: C7H12O7
- Molecular Weight: 208.17
- MDL number: MFCD00005390
- EINECS: 262-037-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-15 13:03:24
What is D-GLUCOHEPTONO-1,4-LACTONE?
Chemical properties
D-GLUCOHEPTONO-1,4-LACTONE is white fine crystalline powder
The Uses of D-GLUCOHEPTONO-1,4-LACTONE
D-GLUCOHEPTONO-1,4-LACTONE is used in the synthesis of Howiinol A and its analogs. D-GLUCOHEPTONO-1,4-LACTONE was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.
The Uses of D-GLUCOHEPTONO-1,4-LACTONE
It is used in the synthesis of Howiinol A and its analogs. Howiinol A was one of the active antitumor constituents from the root and stem bark of Goniothamus howii (Annonaceae), and it was synthesized in 9 steps from α-D-glucoheptonic γ-lactone. Twenty-six analogs were also synthesized in searching for new antitumor compounds with high potency.
Properties of D-GLUCOHEPTONO-1,4-LACTONE
| Melting point: | 152-155 °C(lit.) |
| Boiling point: | 267.35°C (rough estimate) |
| Density | 1.3807 (rough estimate) |
| refractive index | 1.4455 (estimate) |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | DMSO (Slightly), Water (Slightly) |
| pka | 12.05±0.60(Predicted) |
| form | Solid |
| color | White to Pale Beige |
Safety information for D-GLUCOHEPTONO-1,4-LACTONE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for D-GLUCOHEPTONO-1,4-LACTONE
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate 3,6-Dichloropyridazine Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane 4-Morpholinoaniline 2-Chloromethyl-6-methyl-pyridine 1-Indanone tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 2-Pyridinecarboxaldehdye 6-Methyl-2-pyridinemethanol 4-Bromo-2-fluoro-N-methylbenzamide 3-Azetidinecarboxylic acid N-(2-(4-((4-Fluorobenzyl)carbamoyl)-5-hydroxy-6-methoxypyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide (R)-4-Boc-morpholine-3-carboxylic acid (Required high chiral purity NLT:99.5%) Tetrahydro-3-(2-methyl-2- nitropropyl)-2H-pyran-2-one 3-Bromo-2-fluorobenzonitrile Desoximetasone Boron Triiodide Nicotinic acid RAPAMYCIN Pentachlorobenzonitrile BudesonideRelated products of tetrahydrofuran
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