cynaropicrin
- CAS NO.：35730-78-0
- Empirical Formula: C19H22O6
- Molecular Weight: 346.37
- MDL number: MFCD31614147
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is cynaropicrin?
The Uses of cynaropicrin
Cynaropicrin can inhibit lipopolysaccharide-induced TNF-α release from either murine or human macrophage cells in a dose-dependent manner with the IC50 values of 8.24 and 3.18 μM, respectively. It can also inhibit the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.
Definition
ChEBI: Cynaropicrin is a sesquiterpene lactone.
Properties of cynaropicrin
| Boiling point: | 566.2±50.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | -20°C, protect from light |
| solubility | DMSO:50.0(Max Conc. mg/mL);144.35(Max Conc. mM) |
| pka | 13.52±0.10(Predicted) |
| form | Oil |
| color | Off-white to light yellow |
Safety information for cynaropicrin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P501:Dispose of contents/container to..… |
Computed Descriptors for cynaropicrin
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![1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester](https://img.chemicalbook.in/CAS/GIF/50816-24-5.gif)
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