CYCLOPROTHRIN

Synonym(s):(RS)-α-Cyano-3-phenoxybenzyl (RS)-2,2-dichloro-1-(4-ethoxyphenyl)cyclopropanecarboxylate

CAS NO.：63935-38-6
Empirical Formula: C26H21Cl2NO4
Molecular Weight: 482.36
MDL number: MFCD00210269
EINECS: 200-589-5
SAFETY DATA SHEET (SDS)
Update Date: 2025-10-23 17:25:30

What is CYCLOPROTHRIN?

The Uses of CYCLOPROTHRIN

Cycloprothrin is used to control rice water weevils and other insects in paddy rice, fruit, vegetables, tea, cotton, soyabeans and in forestry.

Definition

ChEBI: A carboxylic ester having 2,2-dichloro-1-phenylcyclopropanecarboxylic acid as the acid component and hydroxy(3-phenoxyphenyl)acetonitrile as the alcohol component.

General Description

Cycloprothrin is an insecticide, used for controlling insect pests on rice plants and vegetables.

Metabolic pathway

The structure of the acid moiety of cycloprothrin is rather unusual and thus deserves special attention. The compound has two chiral centres and therefore is a mixture of four stereoisomers; it is used as such. Degradation and metabolism studies have been reported for flooded soil, rice plants and rat. The results show that cycloprothrin is degraded by oxidation, hydrolysis and conjugation reactions as are other members of the class. However, metabolism in rice is very slow.

Degradation

Cycloprothrin is a stable compound but it is hydrolysed under alkaline conditions. It is relatively stable to photodegradation.

Properties of CYCLOPROTHRIN

Melting point:	<25℃
Boiling point:	142.5 °C
Density	1.36±0.1 g/cm3(Predicted)
vapor pressure	2.13×10^-6 Pa (20 °C)
storage temp.	2-8°C
form	neat
Water Solubility	0.09 mg l^-1(25 °C)
BRN	14340823

Safety information for CYCLOPROTHRIN

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H317:Sensitisation, Skin H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.