Cremophor EL
Synonym(s):Cremophor EL;Cremophor ELP;Macrogolglycerol ricinoleate;PEG-35 castor oil;Polyoxyl-35 castor oil
- CAS NO.：61791-12-6
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00130879
- EINECS: 500-151-7
- Update Date: 2026-03-05 13:14:27
What is Cremophor EL?
Chemical properties
light yellow liquid
The Uses of Cremophor EL
Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.
The Uses of Cremophor EL
Kolliphor? EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
General Description
Kolliphor? EL is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Kolliphor? EL is used in lipid-based formulations for drugs and solubilization of cosmetics. Kolliphor EL is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.
Properties of Cremophor EL
| Boiling point: | 232.6℃[at 101 325 Pa] |
| Density | 1.05 g/mL at 20 °C |
| vapor pressure | 0Pa at 25℃ |
| Flash point: | 257℃ |
| storage temp. | REFRIGERATOR (+4C) |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 0[at 20 ℃] |
| form | Viscous Liquid |
| color | Clear yellow |
| PH | 5.0-7.0 (1g/10 mL in H2O) |
| Odor | at 100.00?%. bland |
| Water Solubility | 24.11mg/L at 25℃ |
| Stability: | Stable. Incompatible with storng oxidizing agents. |
| CAS DataBase Reference | 61791-12-6 |
| EPA Substance Registry System | Ethoxylated castor oil (61791-12-6) |
Safety information for Cremophor EL
Computed Descriptors for Cremophor EL
Cremophor EL manufacturer
Bazayan & Co.
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