CP 96345

Synonym(s):(2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine

CAS NO.：132746-60-2
Empirical Formula: C28H32N2O
Molecular Weight: 412.57
MDL number: MFCD00900615
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 01:23:22

What is CP 96345?

The Uses of CP 96345

CP 96345 is a potent and selective non-peptide NK1 receptor antagonist. CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.

The Uses of CP 96345

CP 96345 is a potent and selective non-peptide NK1 receptor antagonist (1,2,3). CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.

What are the applications of Application

CP 96345 is a selective and potent non-peptide NK1receptor antagonist

Biological Activity

Potent and selective non-peptide NK 1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo .

Biochem/physiol Actions

CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.

Storage

Store at -20°C

Properties of CP 96345

storage temp.	room temp
solubility	DMSO: soluble24mg/mL
form	white powder
color	Off-white to light yellow

Safety information for CP 96345

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.