Cortistatin-29 (rat) (trifluoroacetate salt)
- CAS NO.：1815618-17-7
- Empirical Formula: C161H240N46O41S2
- Molecular Weight: 3540.04
- Update Date: 2025-04-18 09:51:29
What is Cortistatin-29 (rat) (trifluoroacetate salt)?
Description
Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-5, respectively. Cortistatin-29 is found at similar levels as cortistatin-14 in mouse AtT20 cells but is secreted at a lower level. Cortistatin-29 corresponds to residues 85-112 of the rat peptide sequence.
Properties of Cortistatin-29 (rat) (trifluoroacetate salt)
| Density | 1.54±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Water: 1 mg/ml |
| form | A lyophilized powder |
Safety information for Cortistatin-29 (rat) (trifluoroacetate salt)
Computed Descriptors for Cortistatin-29 (rat) (trifluoroacetate salt)
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