COCAINE HYDROCHLORIDE
- CAS NO.：53-21-4
- Empirical Formula: C17H22ClNO4
- Molecular Weight: 339.81
- MDL number: MFCD00058119
- EINECS: 200-167-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:14:37
What is COCAINE HYDROCHLORIDE?
Description
Cocaine (hydrochloride) (Item No. 22165) is an analytical reference standard categorized as a tropane. Cocaine has a high potential for abuse and has been found in samples seized by law enforcement. Cocaine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Chemical properties
White Solid
The Uses of COCAINE HYDROCHLORIDE
Inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local)
Definition
ChEBI: The hydrochloride salt of cocaine. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is drug of abuse.
Biological Activity
Competitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with K i values are 267, 392 and 872 nM respectively. Psychostimulant.
Properties of COCAINE HYDROCHLORIDE
| Melting point: | 200-2020C |
| alpha | D -72° (c = 2 in aq soln pH 4.5) |
| storage temp. | 2-8°C |
| solubility | Very soluble in water, freely soluble in alcohol, slightly soluble in methylene chloride. |
| form | Powder |
| Water Solubility | Soluble to 100 mM in water |
| CAS DataBase Reference | 53-21-4 |
| EPA Substance Registry System | 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride (1:1), (1R,2R,3S,5S)- (53-21-4) |
Safety information for COCAINE HYDROCHLORIDE
Computed Descriptors for COCAINE HYDROCHLORIDE
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