cis-4-Hydroxy-D-proline
Synonym(s):(2R,4R)-(+)-4-Hydroxy-2-pyrrolidinecarboxylic acid;D -allo-Hydroxyproline
- CAS NO.：2584-71-6
- Empirical Formula: C5H9NO3
- Molecular Weight: 131.13
- MDL number: MFCD00005252
- EINECS: 219-963-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-02-25 19:46:50
What is cis-4-Hydroxy-D-proline?
Chemical properties
white powder
The Uses of cis-4-Hydroxy-D-proline
cis-4-Hydroxy-D-proline (cas# 2584-71-6) is a compound useful in organic synthesis.
What are the applications of Application
cis-4-Hydroxy-D-proline is a substrate that may be used to study the specificity and kinetics of D-alanine dehydrogenase
Definition
ChEBI: D-proline in which a hydrogen at the 4-position of the pyrrolidine ring is substituted by a hydroxy group (R-configuration).
Biochem/physiol Actions
Cis-4-Hydroxy-D-proline may be used as a starting material for the 13-step synthesis of new conformationally restricted PNA adenine monomer and the synthesis of N-Benzyl pyrrolidinyl sordaricin derivatives. Cis-4-Hydroxy-D-proline is a substrate that may be used to study the specificity and kinetics of D-alanine dehydrogenase. Cis-4-Hydroxy-D-proline may be used to analyze the substrate specificity of amino acid transporter PAT1.
Properties of cis-4-Hydroxy-D-proline
| Melting point: | 243 °C (dec.)(lit.) |
| Boiling point: | 242.42°C (rough estimate) |
| alpha | 58 º (c=2, water 24 ºC) |
| Density | 1.3121 (rough estimate) |
| refractive index | 1.4300 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Water (Slightly) |
| form | Powder |
| pka | 2.14±0.40(Predicted) |
| color | White |
| Water Solubility | 5 g/100 mL |
| BRN | 81439 |
| CAS DataBase Reference | 2584-71-6(CAS DataBase Reference) |
Safety information for cis-4-Hydroxy-D-proline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for cis-4-Hydroxy-D-proline
| InChIKey | PMMYEEVYMWASQN-QWWZWVQMSA-N |
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