Cilazapril Monohydrate
- CAS NO.：92077-78-6
- Empirical Formula: C22H31N3O5.H2O
- Molecular Weight: 435.51
- MDL number: MFCD01692810
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is Cilazapril Monohydrate?
Description
Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.
Chemical properties
White or almost white, crystalline powder.
Originator
Hoffmann-LaRoche (Switzerland)
The Uses of Cilazapril Monohydrate
Antihypertensive.
Definition
ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.
brand name
Inhibace (Hoffmann-LaRoche).
Properties of Cilazapril Monohydrate
| Melting point: | 98° (dec) |
| alpha | D20 -62.51° (c = 1% in ethanol) |
| storage temp. | Store at -20°C |
| solubility | Slightly soluble in water, freely soluble in methanol and in methylene chloride. |
| form | neat |
| pka | pKa1 3.3; pKa2 6.4(at 25℃) |
| form | Solid |
| color | White to off-white |
Safety information for Cilazapril Monohydrate
Computed Descriptors for Cilazapril Monohydrate
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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