CI 1020
Synonym(s):α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt
- CAS NO.：162256-50-0
- Empirical Formula: C28H26O9
- Molecular Weight: 506.5
- MDL number: MFCD00867525
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is CI 1020?
The Uses of CI 1020
A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.
What are the applications of Application
CI 1020 is a highly selective non-peptide ETAR antagonist
Biological Activity
Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.
Properties of CI 1020
| storage temp. | Store at +4°C |
| solubility | Soluble to 50 mM in DMSO |
| form | Powder |
Safety information for CI 1020
Computed Descriptors for CI 1020
New Products
Ivermectin Ep Impurity- k Cyclopropane-1,1-dicarboxylic acid [1]Benzothieno[2,3-c]pyridine, 1,7-dichloro-8-methyl- (S)-3-Fluoro-pyrrolidine hydrochloride Cyclobutylamine 1-Bromo-2-Methoxy-3-Nitrobenzene 3-Oxocyclobutane-1-carboxylicacid (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo [2,3-d]pyrimidine-6-carbox amide 4-amino-2-fluoro-N- methylbenzamide N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one 4-Bromo-2-fluoro-N-methylbenzamide N-Boc-1,4-butanediamine 4-Dimethylamino pyridine 2-Chlorotrityl Chloride 4-Bromoaniline 5-Bromo-2-chlorobenzoic acid 1,2,3,9-Tetrahydro-4(H)-carbazol-4-oneRelated products of tetrahydrofuran
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