CI 1020

Synonym(s):α-[2-(4-Methoxyphenyl)-2-oxo-1-[(3,4,5-trimethoxyphenyl)methyl]ethylidene]-1,3-benzodioxole-5-acetic acid sodium salt

CAS NO.：162256-50-0
Empirical Formula: C28H26O9
Molecular Weight: 506.5
MDL number: MFCD00867525
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-22 18:57:36

What is CI 1020?

The Uses of CI 1020

A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.

What are the applications of Application

CI 1020 is a highly selective non-peptide ETAR antagonist

Biological Activity

Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.

Properties of CI 1020

storage temp.	Store at +4°C
solubility	Soluble to 50 mM in DMSO
form	Powder

Safety information for CI 1020

Computed Descriptors for CI 1020

New Products

Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2,6-Dipicolic Acid 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione MEHYL AMINE-D3.HCL METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-(3-Chlorophenyl)piperazine hydrochloride

Related products of tetrahydrofuran

BENZYL TIGLATE

ANISYL PHENYLACETATE

Ethyl 2-phenylacrylate

1'-hydroxyestragole

2-METHYL-1-PHENYL-2-PROPEN-1-OL

5-HYDROXY-4-METHYL-2(5H)FURANONE

1-PHENYL-2-BUTEN-1-OL

2-PHENYL-2-PENTENAL